Why do we do what we do? The answer lies in this crossword.

The answer to the crossword question is “NATURE.” When combined with the hint given in 58-Across, the phrase “why we do what we do is HUMAN” suggests that the answer is related to the inherent traits or characteristics that make us human. In other words, it is in our nature to behave in certain ways and make certain choices. This idea is well-supported by research in psychology, biology, and other fields, which have shown that human behavior is influenced by a complex interplay of genetics, environment, and individual experiences. Therefore, the answer “NATURE” fits well with the context of the clue and supports the theme of the puzzle.