The answer to this crossword question is ALCOA, which is a Pittsburgh-based giant in the metals industry. ALCOA is a global leader in the production of aluminum, titanium, and other metals, and it has a long history of innovation and excellence in the industry. Founded in 1888, ALCOA has grown to become one of the largest and most respected companies in the metals industry, with operations in more than 30 countries around the world. The company is known for its commitment to sustainability and environmental responsibility, and it has received numerous awards and accolades for its efforts in these areas. Overall, ALCOA is a major player in the metals industry, and its presence in Pittsburgh and around the world is a testament to its success and leadership in the field.