As a detective solving the mystery of the crossword clue “Passage straight from the heart,” my mind immediately went to the anatomy of the heart. I considered the various arteries and veins that connect to and from the heart, and after analyzing the clue, I decided that the passage in question had to be a major artery. I then thought of the Aorta, the largest artery in the body that originates directly from the heart’s left ventricle, representing the straight passage straight from the heart. The word ‘straight‘ in the clue played a crucial role in my deduction, as it hinted at an arterial route that is not crooked, but straight. Therefore, with all these clues pointing in one direction, I confidently identified the answer as ‘AORTA.’ The mastery of language and the intricacies of the human body always make crossword puzzles an intriguing enigma to solve.