As a detective attempting to solve the mystery of the crossword clue ‘Kickoff‘, I first considered all of the possible meanings of the word ‘kickoff‘. While ‘kickoff‘ can most commonly refer to the beginning of a football game, it can also refer to the start of any type of event or activity. Keeping this in mind, I started searching for possible answers that would fit the clue. After considering several possibilities, it became clear that the word ‘START‘ was the perfect solution to this particular crossword puzzle. Not only does it fit the definition of ‘kickoff‘, it is a commonly used synonym that is often associated with the beginning of anything from a project to a race. With this insight, I was able to successfully solve the crossword clue and move on to the next challenge.