Early Bond villain

The crossword question refers to the first James Bond movie “Dr. No” released in 1962, which featured Sean Connery as James Bond and Joseph Wiseman as the main villain Dr. No. Dr. No is a scientific genius who works for the criminal organization SPECTRE and plans to disrupt a US space launch as part of his plan to start a war between the US and the Soviet Union. The character is memorable for his distinctive accent, metal hands, and radiation suit, and is considered a classic Bond villain. The film was a huge success and launched the long-running James Bond movie franchise, with Dr. No setting the standard for future Bond villains.