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The crossword clue ‘Bother’ can be answered with the word ‘Pain’. Pain is a type of unpleasant sensation or discomfort experienced by an individual. It is a subjective feeling that can vary in intensity from mild to severe, and is often caused by some kind of physical or emotional injury or trauma.

When we experience pain, it can be accompanied by a range of physical symptoms such as swelling, redness, or tenderness. Depending on the severity of pain, it can cause a person to feel uncomfortable, irritable or even become unable to perform daily activities. Pain can be acute, meaning it lasts for a short period of time or chronic, lasting for weeks, months or even years.

Pain is often categorized based on its location in the body such as head pain, back pain, stomach pain etc or as neuropathic, musculoskeletal and other types. Treatment for pain can vary depending on its cause and can involve medication, physiotherapy and surgery.

So, in conclusion, the crossword clue ‘bother’ can be answered with the word ‘pain’ which is an unpleasant sensation or discomfort experienced by an individual due to physical or emotional injury or trauma.