As a detective solving the mystery of the crossword clue ‘Abruptly resign‘, my first step was to consider the number of letters required for the answer. In this case, it was six letters, suggesting that the solution could be two words consisting of three letters each. Next, I focused on the word ‘abruptly‘, which hinted at the idea of something sudden or unexpected. This led me to think of phrases such as ‘throw in the towel‘ or ‘give up‘, which are commonly used to describe resigning suddenly. However, these phrases had too many letters to fit the required space in the crossword puzzle. Finally, I hit upon the solution: ‘UPANDQUIT‘. This phrase perfectly captures the sudden and unexpected nature of the clue and also fits the required space. With this insight, I confidently filled in the answer and solved the crossword puzzle.